Choose one short story studied in Weeks 3 and 4 and provide a personal and scholarly interpretation of this short story in relation to its literary genre. Your interpretation will….
What are some of the potential ethical problems with this study?
Investigators sponsored by the NIH and private foundation are conducting an HIV vaccine trial in a sub-Saharan African nation. In the trial, HIVnegative adolescents will be randomized to receive either an experimental vaccine or a placebo. They will be instructed on ways to prevent HIV infection and provided with condoms. They will be followed for fi ve years to see if either group has a higher HIV infection rate. They will be tested for HIV on a regular basis and interviewed concerning their sexual activities and other risky behaviors. If they develop HIV, they will be treated according to the standard of care in the sub-Saharan nation, which includes access to only some of the HIV medications available in the developing world. Subjects who develop HIV will receive free medication for a maximum of one year. There are no plans to compensate subjects for research-related injuries. Interviews with some of the subjects participating in the trial revealed a profound lack of understanding of the purpose of the study and its procedures. Many participants thought they were receiving treatment for HIV rather than an HIV vaccine. A data monitoring committee found that people who received the vaccine had an increased risk for arthritis and diabetes.
• What are some of the potential ethical problems with this study?
• Should an HIV vaccine be tested on adolescents?