- Compare and contrast findings from 4 – 5 original journal articles published in the last ten years (e.g. 2007 or later) that describe molecular diagnosis of a genetic condition.
- You will need to reference your chosen articles, and you should also use other articles to help to put the topics into context.
- Introduce the disease (genes involved, outcomes) but focus mainly on the MOLECULAR techniques used in diagnosing the disease
why these are appropriate
• advantages and disadvantages of the approaches used • discuss if there is conflicting information or data.
- Breast cancer (genetic, e.g. BRCA1/BRCA2)
- However, you can choose any disease you like that we haven’t covered in class AND
- there is enough information/recent papers for you to be able to do the assignment. There is a 2-part submission process. This is partly to encourage you to start the assignment early and partly to allow you to receive feedback on your essay plan
PART 1 (Worth 5%) Written assignment – essay plan & endnote library
This “pre-submission” will consist of:
| 1.
|
A preliminary Endnote Library containing your references. This will include your four – five main references,
and may include other papers you have used to help you with background reading
|
5 marks
|
| 2. | An essay plan (1 page minimum, 2 page maximum)
This can be with subheadings and in point form
E.g
. Introduction: disease, clinical features, incidence, types of genetic diagnostic techniques you will be addressing in the essay Main body: compare and contrast the three diagnostic methods used in the the papers. Include the technology use and the advantages/disadvantages of each Conclusion: You may not have much to say here yet, as you are still working on this assignment
|
10 marks |
| 3.
|
A reflection (200-250 words)
In this section you can write about why you choose the topic you did; has it been easy/difficult to find the information; did you change topic? Is it interesting? Why or why not?
|
5 marks
|
| TOTAL |
20 marks |
Formatting requirements
Please use Arial, Calibri, or Times New Roman, font size 12 2.5 cm margins top and bottom, 2 cm margins left and right 1.5 spacing
PART 2 (Worth 25%)
The final submission will comprise:
- Afinal Endnote Library & appropriate referencing
- The final written assignment (maxof2500words)
- Graphical abstract. For more information on graphical abstracts- https://www.elsevier.com/authors/journal-authors/graphical-abstract
