1.
a. Highlight forms of non-adherence in the fight against HIV and AIDS. (4 marks)
b. Describe how biological markers are applied in effectiveness of HIV and AIDS treatment. (3 marks)
2.
a. Outline four approved classes of drugs in the HAART regimens. (4 marks)
b. Drug “holidays” or treatment interruptions result in rapid viral rebound within 2 to 3 weeks of treatment discontinuation. Explain. (3 marks)
3. Describe the stages of HIV life cycle under the following sub headings.
a. Transcription
b. Assembly
c. Integration
4.
a. What is acute retroviral syndrome. (2 marks)
b. Discuss symptoms of acute reteoviral syndrome. (5 marks)
5. Describe the administration of combined AZT (efavirenz) and NVP (Nevirapine), the recommended course of drugs for preventing mother to child trnasmission (PMTCT) in resources-limited settings. (7 marks)
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