This section is worth 50 marks. Each question is worth 10 marks.
Please answer the following 5 questions (adhering to plagiarism rules).
Diagrams, tables, flowcharts can be included in your answer (do not exceed 500 words/question).

QUESTION 1
A young girl has touched a hot plate on the stovetop and has developed blisters. Describe the sequence of events that occur following a mild thermal burn to the hand. Correlate the clinical signs with the microscopic pathological processes and outline the possible outcomes of such an injury.
QUESTION 2
A motorcyclist has sustained many injuries following a traffic accident, one of which includes a compound bone fracture of the tibia. Describe the sequence of events that follow a compound bone fracture of the tibia and discuss the factors that may delay healing.
QUESTION 3
A young boy was admitted to hospital with respiratory difficulties and a suspected asthma attack. He also appears to have a rash on his hands consistent with contact dermatitis. Describe the pathogenetic mechanisms underlying his clinical disease states.
QUESTION 4
An adolescent girl has been diagnosed with malnourishment but appears to be retaining much fluid around the body. Discuss the aetiology and pathogenesis of this fluid retention.
QUESTION 5
An elderly woman has been diagnosed with deep vein thrombosis following a long flight overseas. What is “thrombosis”? Discuss the various aetiological and clinical risk factors associated with this condition. In your answer, include the relationship between thrombosis, atherosclerosis and infarction.

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