Compare Darwin’s description of natural selection as quoted on page 765 with Wallace’s description of the tendency of varieties to depart from the original type quoted below it, on the same page. What ideas do they have in common? What are the three principles of the theory of evolution by natural selection? Why was the neutral theory of molecular evolution a revolutionary idea? What would you predict to be the relative rate of synonymous and nonsynonymous substitutions in a globin pseudogene? Are AS heterozygotes completely resistant to malarial infection? Explain the evidence for your answer.