A prospective cohort study of psychiatric outpatients with a history of suicidal ideation was conducted, investigating the effect of alcohol consumption and incidence of attempted suicide over a follow-up period of 24 months. The data at the end of the follow-up period for males and females are given below.

 

Males

Alcohol consumption Cases Participants
Light 5 250
Heavy 23 375

 

Females

Alcohol consumption Cases Participants
Light 25 250
Heavy 52 167

 

Assume no loss to follow-up and that all participants were followed over the follow-up period.

 

Discuss statistical interaction and confounding by sex for the following effect measures

 

-Risk difference

-Risk ratio

-Odds ratio

 

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